[HTML][HTML] … uptake of oxidized and acetylated low-density lipoproteins and generation of reactive oxygen species are regulated by linear stiffness of the growth surface
… atherosclerosis develops due to progressive accumulation of … mRNA expression of the
cholesterol efflux transporters ATP-… with the rho-associated coiled coil kinase (ROCK)1/2 inhibitor…
cholesterol efflux transporters ATP-… with the rho-associated coiled coil kinase (ROCK)1/2 inhibitor…
Targeting ROCK signaling in health, malignant and non-malignant diseases
R Shahbazi, B Baradaran, M Khordadmehr, S Safaei… - Immunology letters, 2020 - Elsevier
… A Rho-associated coiled-coil kinase (ROCK) is identified as … lesions of atherosclerosis and
the formation of foam cells. The … mutations in ROCK2 can lead to increased kinase activity [9]. …
the formation of foam cells. The … mutations in ROCK2 can lead to increased kinase activity [9]. …
[HTML][HTML] The physiology, pathology, and therapeutic interventions for ROCK isoforms in diabetic kidney disease
K Matoba, Y Takeda, Y Nagai, K Sekiguchi… - Frontiers in …, 2020 - frontiersin.org
… Rho-associated coiled-coil-containing protein kinase (ROCK… Due to its centrality in most
cellular events, robust … and cubulin, members of the low-density lipoprotein receptor family that …
cellular events, robust … and cubulin, members of the low-density lipoprotein receptor family that …
[HTML][HTML] … knockdown alleviates oxidized low‑density lipoprotein‑induced cell injury and inflammatory responses in human umbilical vein endothelial cells via the miR …
J Miao, B Wang, R Shao… - … journal of molecular …, 2021 - spandidos-publications.com
… cells (HUVECs) are important features of atherosclerosis (AS)… blot analysis or enzyme‑linked
immunosorbent assay (ELISA)… ‑20a‑5p and Rho‑associated coiled‑coil kinase 2 (ROCK2) …
immunosorbent assay (ELISA)… ‑20a‑5p and Rho‑associated coiled‑coil kinase 2 (ROCK2) …
[HTML][HTML] QiShenYiQi pill inhibits atherosclerosis by promoting reverse cholesterol transport PPARγ-LXRα/β-ABCA1 pathway
J Xie, L Peng, C Yang, N Chen, X Feng, T Wu… - Journal of …, 2023 - Elsevier
… for QSYQ inhibiting atherosclerotic plaque is due to reduce lipid … during atherosclerosis, our
results found that QSYQ reduced … cholesterol efflux in human myeloid leukemia mononuclear …
results found that QSYQ reduced … cholesterol efflux in human myeloid leukemia mononuclear …
Regulation of oxidized LDL-induced proliferation and migration in human vascular smooth muscle cells by a novel circ_0007478/miR-638/ROCK2 ceRNA network
Z Guan, R Lu, Y Sun, X Wang, C Yu… - Vascular …, 2023 - journals.sagepub.com
… smooth muscle cells (VSMCs) under oxidized low-density … )-638, and rho-associated
protein kinase 2 (ROCK2) levels … -638 is tightly linked to vulnerable atherosclerotic plaques in …
protein kinase 2 (ROCK2) levels … -638 is tightly linked to vulnerable atherosclerotic plaques in …
Regulation of efferocytosis by caspase-dependent apoptotic cell death in atherosclerosis
… against atherosclerosis, since it leads to reduced cellularity of … Rho-associated coiled-coil-containing
protein kinase 1 (… ApoE −/− mice bone marrow-derived macrophages (BMDM) and …
protein kinase 1 (… ApoE −/− mice bone marrow-derived macrophages (BMDM) and …
[HTML][HTML] Endothelial Function in dyslipidemia: roles of LDL-cholesterol, HDL-cholesterol and triglycerides
Y Higashi - Cells, 2023 - mdpi.com
… Endothelial dysfunction is the initial step for atherosclerosis … an increase in Rho-associated
kinase activity and a decrease … oxidation, decrease in oxidative stress, cholesterol efflux from …
kinase activity and a decrease … oxidation, decrease in oxidative stress, cholesterol efflux from …
ROCK inhibition may stop diabetic kidney disease
K Matoba, Y Takeda, Y Nagai, Y Kanazawa… - JMA journal, 2020 - jstage.jst.go.jp
… Rho-associated coiled-coilcontaining kinase 2 deficiency in bone marrow-derived cells
leads to increased cholesterol efflux and decreased atherosclerosis. Circulation. 2012;126(18):…
leads to increased cholesterol efflux and decreased atherosclerosis. Circulation. 2012;126(18):…
[HTML][HTML] Monocyte-endothelial cell interactions in vascular and tissue remodeling
M Medrano-Bosch, B Simón-Codina… - Frontiers in …, 2023 - frontiersin.org
… activating RHO-associated coiled-coil containing protein kinase … and differentiation of bone
marrow-derived cells (BMCs). … target and treat macrophages in experimental atherosclerosis. …
marrow-derived cells (BMCs). … target and treat macrophages in experimental atherosclerosis. …